Large quantities of stem cells exist in our fat. The part of our fat that is rich in stem cells and valuable growth factors is called SVF (Stromal Vascular Fraction). By removing fat through a mini-liposuction process or even a more extensive liposuction surgery you can isolate large quantities of your own stem cells in SVF that can be used during the same surgical procedure and/or stored in a deep freeze (“cryopreserved”) for later use.
While we may commonly think of stem cells as being associated with embryonic tissue, they can be found in nearly every adult organ. A stem cell is simply an unspecialized cell that has the ability to 1) replicate and 2) differentiate (change) into another specific kind of cell. In our adult bodies they represent “spare parts” so that when called upon because of cell injury or cell death, the stem cell can be “signaled” to replace the specific cell with “like” tissue. Most injuries repair with a degree of scarring as white blood cells are typically summoned to an injury in much greater quantities than stem cells. Your white blood cells can then transform into fibroblasts that end up forming scar tissue. Stem cells can actually transform into the cell that has been injured.
While there are a variety of sources for stem cells, fat (also known as adipose tissue) generally has a huge abundance of these special cells. While bone marrow stem cells are commonly used for many adult conditions, 120cc of bone marrow may yield 60,000 stem cells. Fat, on the other hand, may yield millions of stem cells from just 25cc of condensed fat. For most people this simply means performing a 5 to 10 minute procedure under straight local anesthesia to harvest 1 to 2 ounces of fatty tissue. The stem cells in fat are found largely as “pre-adipocytes” mixed among the fat cells and also as a multitude of cells within and surrounding the walls of the blood vessels that course through our fat cells. There are other cells found within fatty tissue too as part of the SVF – including white blood cells, red blood cells, T-regulatory cells, endothelial cells, platelets and growth factors. SVF contains no actual fat after processing.
Today, a number of physicians are already treating patients with their own SVF for a variety of inflammatory and degenerative conditions. In fact, Cells on Ice grew following the successful growth of the CSN Cell Surgical Network. This organization continues to teach doctors worldwide how to safely procure and prepare SVF via a mini-liposuction procedure with preparation of the cells done under a completely closed sterile surgical procedure. While many conditions may possibly be repaired with a single SVF treatment, there are a number of conditions that may require multiple interventions. In such cases, having a larger quantity of SVF cells stored (cryopreserved) would enable the patient to get cells repeatedly without having to undergo the mini-liposuction procedure each time. This provides a convenience and also a cost savings.
Because of regulatory restrictions, there are limits to claims that can be made with respect to your own adipose derived SVF. Nonetheless, the Cell Surgical Network and other reputable networks and clinicians, are gathering a lot of empirical clinical data to show SVF administration is both safe and effective. CSN has deployed SVF into thousands of patients for a variety of autoimmune and degenerative conditions. The initial safety study by CSN on 1524 patients showed there were no serious or significant adverse events directly related to SVF deployment.